High SNHG expression may predict a poor lung cancer prognosis based on a meta-analysis

Shen, Guo-yi; Huang, Rong-zhi; Yang, Shao-bin; Shen, Rong-qiang; Gao, Jian-li; Zhang, Yi

doi:10.1186/s12885-023-11706-4

BMC Cancer

Table 1 Basic features of the publications included in this meta-analysis (n = 40)

From: High SNHG expression may predict a poor lung cancer prognosis based on a meta-analysis

Author and year	Sample size	Level of expression	Detection methods	Cut-off value	Reference gene	Survival outcome	HR with 95%CI	LCI	UCI	Analysis methods	Follow-up (month)	NOS score
Wei L 2019	64	upregulated	qRT-PCR	median	GAPDH	OS	2.56	1.2	5.47	Univariate analysis	24	8
Cui Y 2017	68	upregulated	qRT-PCR	median	GAPDH	OS	2.07	1.13	3.79	Univariate analysis	60	8
Li XM 2020	40	upregulated	qRT-PCR	mean	GAPDH	Not reported	-	-	-	-	-	7
Zhang HY 2017	36	upregulated	qRT-PCR	mean	GAPDH	Not reported	-	-	-	-	-	7
Li CL 2019	64	upregulated	qRT-PCR	mean	GAPDH	Not reported	-	-	-	-	-	7
Yang XH 2021	41	downregulated	qRT-PCR	mean	GAPDH	Not reported	-	-	-	-	-	7
Kang BJ 2021	66	downregulated	qRT-PCR	mean	GAPDH	Not reported	-	-	-	-	-	7
Zhao LJ 2021	35	upregulated	qRT-PCR	median	GAPDH	Not reported	-	-	-	-	-	7
Shi JD 2019	32	upregulated	qRT-PCR	median	GAPDH	OS	2.71	0.99	7.41	Univariate analysis	60	8
Zhao SS 2020	42	upregulated	qRT-PCR	Not reported	GAPDH	OS	2.16	0.73	6.38	Univariate analysis	60	7
Wang F 2021	50	upregulated	qRT-PCR	mean	GAPDH	OS	1.79	0.67	4.8	Univariate analysis	60	8
Wang F 2021	50	upregulated	qRT-PCR	mean	GAPDH	DFS	2.03	0.97	4.27	Univariate analysis	60	8
Gao N 2020	45	upregulated	qRT-PCR	mean	GAPDH	OS	2.34	1.19	4.61	Univariate analysis	60	6
Dong Z 2020	40	upregulated	qRT-PCR	mean	GAPDH	OS	2.36	0.9	6.17	Univariate analysis	60	6
Geng H 2020	60	upregulated	qRT-PCR	median	GAPDH	OS	1.76	0.8	3.86	Univariate analysis	36	8
Liang R 2018	60	upregulated	qRT-PCR	mean	GAPDH	OS	2.33	1.23	4.40	Univariate analysis	48	8
Pang LL 2019	42	upregulated	qRT-PCR	mean	GAPDH	Not reported	-	-	-	-	-	7
Li LP 2020	36	upregulated	qRT-PCR	mean	GAPDH	OS	3.85	1.86	10.96	Univariate analysis	60	6
Chen CH 2018	120	upregulated	qRT-PCR	median	β-actin	OS	1.3	0.88	1.9	Univariate analysis	60	8
Chen CH 2018	120	upregulated	qRT-PCR	median	β-actin	PFS	1.24	0.85	1.79	Univariate analysis	60	8
Wang RX 2020	50	upregulated	qRT-PCR	mean	GAPDH	OS	2.55	0.85	7.66	Univariate analysis	48	6
Liu SX 2019	42	upregulated	qRT-PCR	median	GAPDH	OS	2.07	1.04	4.14	Univariate analysis	60	8
Huang YS 2022	65	upregulated	qRT-PCR	mean	GAPDH	OS	2.25	1.05	4.86	Univariate analysis	60	8
Wang Y 2019	40	upregulated	qRT-PCR	median	GAPDH	OS	2.27	0.83	6.19	Univariate analysis	48	6
Wang S 2018	128	upregulated	qRT-PCR	mean	GAPDH	OS	2.1276	1.0638	4.1667	Univariate analysis	60	6
Guo LF 2018	40	upregulated	qRT-PCR	mean	GAPDH	OS	-	-	-	-	-	7
Huang YF 2021	68	upregulated	qRT-PCR	mean	GAPDH	OS	4.09	1.94	8.61	Univariate analysis	48	8
Zhang NN 2021	45	upregulated	qRT-PCR	mean	GAPDH	OS	2.27	0.69	7.41	Univariate analysis	54	8
Chen XL 2020	50	upregulated	qRT-PCR	mean	GAPDH	OS	2.11	0.9	4.96	Univariate analysis	60	8
Zhang ZH 2018	99	upregulated	qRT-PCR	mean	GAPDH	OS	1.66	0.94	2.93	Univariate analysis	60	8
Ma XR 2019	24	upregulated	qRT-PCR	mean	GAPDH	OS	3.298	1.3635	7.9774	Univariate analysis	60	6
Dong YZ 2018	49	upregulated	qRT-PCR	median	GAPDH	OS	1.84	0.94	3.59	Univariate analysis	120	8
Dong YZ 2018	49	upregulated	qRT-PCR	median	GAPDH	DFS	2.22	1.17	4.19	Univariate analysis	80	8
Cui HX 2018	55	upregulated	qRT-PCR	mean	GAPDH	OS	2.234	1.0334	4.8294	Univariate analysis	80	8
Han PF 2021	118	upregulated	qRT-PCR	mean	GAPDH	OS	3.71	1.67	6.94	9	60
Jin B 2018	35	upregulated	qRT-PCR	median	GAPDH	OS	1.63	0.56	4.76	Univariate analysis	60	8
Li Y 2022	30	upregulated	qRT-PCR	mean	GAPDH	Not reported	-	-	-	-	-	7
Han W 2018	66	upregulated	qRT-PCR	mean	β-actin	OS	2.73	1.381	5.397	Multivariate analysis	60	9
Han W 2018	66	upregulated	qRT-PCR	mean	β-actin	DFS	2.641	1.394	5.002	Multivariate analysis	60	9
Zhang ZW 2021	50	upregulated	qRT-PCR	median	GAPDH	OS	2.2	0.93	5.19	Univariate analysis	120	8
Fan HJ 2021	63	upregulated	qRT-PCR	mean	GAPDH	OS	2.459	1.584	4.971	Multivariate analysis	60	9
Jin LL 2019	42	upregulated	qRT-PCR	median	GAPDH	OS	2.46	0.96	6.29	Univariate analysis	60	6
Chen ZY 2017	42	upregulated	qRT-PCR	median	GAPDH	OS	6.06	2.44	15.07	Univariate analysis	24	8
Chen ZY 2017	42	upregulated	qRT-PCR	median	GAPDH	PFS	3.89	1.48	10.22	Univariate analysis	24	8
Wang XL 2020	63	upregulated	qRT-PCR	mean	GAPDH	Not reported	-	-	-	-		7

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