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Table 2 Basic demographics of the patients

From: A practical prognostic peripheral blood-based risk model for the evaluation of the likelihood of a response and survival of metastatic cancer patients treated with immune checkpoint inhibitors

 

All

Risk model

n = 109

n (%)

Low-risk

n = 76

n (%)

High-risk

n = 33

n (%)

P value

n = 158

Low vs.

n (%)

high risk

Sex

    

0.302

Male

108 (68.4%)

75 (68.8%)

50 (65.8%)

25 (75.8%)

 

Female

50 (31.6%)

34 (31.2%)

26 (34.2%)

8 (24.2%)

 

Age

    

0.923

≤ 65 years

76 (48.1%)

47 (43.1%)

33 (43.4%)

14 (42.4%)

 

> 65 years

82 (51.9%)

62 (56.9%)

43 (56.6%)

19 (57.6%)

 

PS (WHO)

    

0.003*

0

92 (58.2%)

66 (60.6%)

53 (69.7%)

13 (39.4%)

 

≥ 1

66 (41.8%)

43 (39.4%)

23 (30.3%)

20 (60.6%)

 

Cancer type

    

0.288

NSCLC

75 (47.5%)

52 (47.7%)

37 (48.7%)

15 (45.5%)

 

Melanoma

28 (17.7%)

19 (17.4%)

16 (21.1%)

3 (9.1%)

 

RCC

26 (16.5%)

19 (17.4%)

10 (13.2%)

9 (27.3%)

 

Head and neck

8 (5.1%)

7 (6.4%)

3 (3.9%)

4 (12.1%)

 

MSI high

7 (4.4%)

5 (4.6%)

4 (5.3%)

1 (3.0%)

 

Urothelial

8 (5.1%)

4 (3.7%)

3 (3.9%)

1 (3.0%)

 

Lymphoma

5 (3.2%)

2 (1.8%)

2 (2.6%)

0 (0%)

 

TNBC

1 (0.6%)

1 (0.9%)

1 (1.3%)

0 (0%)

 

Metastatic sites

     

Lymph nodes

104 (65.8%)

71 (65.1%)

46 (60.5%)

25 (75.8%)

0.125

Lung

89 (56.3%)

60 (55.0%)

44 (57.9%)

16 (48.5%)

0.364

Bone

47 (29.7%)

33 (30.3%)

17 (22.4%)

16 (48.5%)

0.006*

Liver

33 (20.9%)

27 (24.8%)

16 (21.1%)

11 (33.3%)

0.172

Brain

17 (10.8%)

12 (11.0%)

8 (10.5%)

4 (12.1%)

0.752

  1. PS, performance status; WHO, World Health Organization; NSCLC, non-small cell lung cancer; RCC, renal cell carcinoma; MSI, microsatellite instability; TNBC, triple negative breast cancer; *p < 0.05