Variables | Univariate analysis | Â | Multivariate analysis | ||
---|---|---|---|---|---|
HR (95% CI) | P Value | Â | HR (95% CI) | P Value | |
Sex | Â | Â | Â | Â | Â |
 Male | Reference |  |  | Reference |  |
 Female | 0.839 (0.739–0.952) | 0.006 |  | 0.851 (0.728–0.995) | 0.043 |
Age | Â | Â | Â | Â | Â |
 ≤ 45 | Reference |  |  | Reference |  |
 46–60 | 1.423 (1.122–1.805) | 0.004 |  | 1.397 (1.100-1.774) | 0.006 |
 61–75 | 1.723 (1.361–2.182) | < 0.001 |  | 1.493 (1.175–1.896) | 0.001 |
 > 75 | 2.378 (1.768–3.198) | < 0.001 |  | 1.861 (1.376–2.516) | < 0.001 |
Region | Â | Â | Â | Â | Â |
 Eastern | Reference |  |  | Reference |  |
 Southern | 1.261 (1.011–1.572) | 0.039 |  | 1.304 (1.045–1.628) | 0.019 |
 Western | 0.685 (0.583–0.804) | < 0.001 |  | 0.726 (0.616–0.855) | < 0.001 |
 Northern | 0.909 (0.785–1.052) | 0.199 |  | 0.926 (0.799–1.073) | 0.306 |
Hospital | Â | Â | Â | Â | Â |
 Specialized | Reference |  |  |  |  |
 General | 1.032 (0.884–1.204) | 0.693 |  |  |  |
Health insurance | Â | Â | Â | Â | Â |
 Urban employees’ basic medical insurance | Reference |  |  |  |  |
 Urban residents’ basic medical insurance | 0.986 (0.810–1.200) | 0.885 |  |  |  |
 New rural cooperative medical scheme | 0.972 (0.853–1.108) | 0.673 |  |  |  |
 Self-pay | 1.069 (0.794–1.440) | 0.660 |  |  |  |
 Other | 0.687 (0.409–1.154) | 0.156 |  |  |  |
Smoke | Â | Â | Â | Â | Â |
 No | Reference |  |  | Reference |  |
 Yes | 1.159 (1.034–1.298) | 0.011 |  | 1.025 (0.89–1.182) | 0.729 |
Alcohol use | Â | Â | Â | Â | Â |
 No | Reference |  |  |  |  |
 Yes | 1.074 (0.955–1.208) | 0.231 |  |  |  |
TNM Stage | Â | Â | Â | Â | Â |
 I | Reference |  |  | Reference |  |
 II | 1.152 (0.830–1.597) | 0.398 |  | 1.116 (0.797–1.561) | 0.523 |
 III | 1.468 (1.108–1.944) | 0.007 |  | 1.471 (1.094–1.978) | 0.011 |
 IV | 2.142 (1.620–2.832) | < 0.001 |  | 1.977 (1.469–2.66) | < 0.001 |
Surgery | Â | Â | Â | Â | Â |
 No | Reference |  |  | Reference |  |
 Yes | 0.563 (0.439–0.721) | < 0.001 |  | 0.675 (0.519–0.879) | 0.003 |
Chemotherapy | Â | Â | Â | Â | Â |
 No | Reference |  |  | Reference |  |
 Yes | 0.674 (0.589–0.770) | < 0.001 |  | 0.707 (0.616–0.813) | < 0.001 |
Radiotherapy | Â | Â | Â | Â | Â |
 No | Reference |  |  | Reference |  |
 Yes | 0.775 (0.681–0.882) | < 0.001 |  | 0.803 (0.702–0.917) | < 0.001 |