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Table 1 Relationships between clinicopathological data and PSMD1 expression

From: PSMD1 as a prognostic marker and potential target in oropharyngeal cancer

Variables

n

Low PSMD1

High PSMD1

P value

Gender

   

.000

 Male

59

48 (92.3%)

11 (91.7%)

 

 Female

5

4 (7.7%)

1 (8.3%)

 

Smoking

   

.101

 (-)

26

24 (46.2%)

2 (16.7%)

 

 (+)

38

28 (53.8%)

10 (83.3%)

 

Alcohol

   

.778

 (-)

29

24 (46.2%)

5 (41.7%)

 

 (+)

35

28 (53.8%)

7 (58.3%)

 

Age > 60

   

.778

 > 60

29

24 (46.2%)

5 (41.7%)

 

 < 60

35

28 (53.8%)

7 (58.3%)

 

Location

   

.002

 Tonsil

46

42 (80.8%)

4 (33.3%)

 

 Others

18

10 (19.2%)

8 (66.7%)

 

Pathologic T stage

   

.351

 T1-2

55

46 (88.5%)

9 (75.0%)

 

 T3-4

9

6 (11.5%)

3 (25.0%)

 

Pathologic N stage

   

.810

 N0-1

30

24 (46.2%)

6 (50.0%)

 

 N2-3

34

28 (53.8%)

6 (50.0%)

 

Overall stage

   

.005

 I-II

52

45 (86.5%)

6 (50.0%)

 

 III-IV

12

7 (13.5%)

6 (50.0%)

 

Differentiation

   

.463

 Class 1–2

38

32 (61.5%)

6 (50.0%)

 

 Class 3

26

20 (38.5%)

6 (50.0%)

 

Lymphovascular invasion

   

.751

 (-)

39

31 (59.6%)

8 (66.7%)

 

 (+)

25

21 (40.4%)

4 (33.3%)

 

Perineural invasion

   

.252

 (-)

59

49 (94.2%)

10 (83.3%)

 

 (+)

5

3 (5.8%)

2 (16.7%)

 

Extranodal extension

   

.476

 (-)

21

15 (51.7%)

6 (66.7%)

 

 (+)

17

14 (48.3%)

3 (33.3%)

 

Size

   

.115

 < 4 cm

57

48 (92.3%)

9 (75.0%)

 

 > 4 cm

7

4 (7.7%)

3 (25.0%)

 

Surgical margin

   

.714

 Free/close

48

38 (73.1%)

10 (83.3%)

 

 Involved

16

14 (26.9%)

2 (16.7%)

 

HPV

   

.016

 (-)

15

9 (17.3%)

6 (50.0%)

 

 (+)

49

43 (82.7%)

6 (50.0%)

 

Recurrence

   

.314

 (-)

45

38 (73.1%)

7 (58.3%)

 

 (+)

19

14 (26.9%)

5 (41.7%)

 

Surgical intent

   

.196

 Curative

53

45 (86.5%)

8 (66.7%)

 

 Salvage

11

7 (13.5%)

4 (33.3%)

 

Postoperative Radiotherapy

   

.314

 (-)

19

14 (26.9%)

5 (41.7%)

 

 (+)

45

38 (73.1%)

7 (58.3%)

 
  1. Fisher’s exact test and Pearson’s chi-square test were applied where appropriate. (HPV, Human papillomavirus)