Fig. 8From: Regulatory function and mechanism research for m6A modification WTAP via SUCLG2-AS1- miR-17-5p-JAK1 axis in AMLmiR-17-5p regulates the occurrence and development of AML through JAK1. AÂ The negative regulatory effect of miR-17-5p on JAK1 expression levels in AML cells was detected by qRT-PCR. BÂ The negative regulatory effect of miR-17-5p on JAK1 expression levels in AML cells was detected by WB. C, DÂ SUCLG2-AS1 can affect the proliferation of AML cells through miR-17-5p by CCK-8 assay and EdU assay. EÂ miR-17-5p can affect the migration and invasion of AML cells through JAK1 by Transwell assay. FÂ miR-17-5p can regulate the apoptosis of AML cells through JAK1 by flow cytometryBack to article page