Skip to main content
Fig. 6 | BMC Cancer

Fig. 6

From: Regulatory function and mechanism research for m6A modification WTAP via SUCLG2-AS1- miR-17-5p-JAK1 axis in AML

Fig. 6

SUCLG2-AS1 functioned via negatively regulating miR-17-5p expression in AML cells. A The regulatory function of SUCLG2-AS1 on the expression level of miR-17-5p in AML cells. B The luciferase reporter assay validated the relationships between SUCLG2-AS1 and miR-17-5p. C Ago2 RNA-binding protein immunoprecipitation assay to verify SUCLG2-AS1 binding with miR-17-5p. D, E SUCLG2-AS1 can affect the proliferation of AML cells through miR-17-5p by CCK-8 assay and EdU assay. F SUCLG2-AS1 can affect the migration and invasion of AML cells through miR-17-5p by Transwell assay. G SUCLG2-AS1 can regulate the apoptosis of AML cells through miR-17-5p by flow cytometry

Back to article page