Skip to main content
Fig. 3 | BMC Cancer

Fig. 3

From: Regulatory function and mechanism research for m6A modification WTAP via SUCLG2-AS1- miR-17-5p-JAK1 axis in AML

Fig. 3

Screening key genes from ceRNA network and functional analysis. A Construction of a lncRNA-miRNA-mRNA ceRNA network for AML. In the ceRNA network, the blue and red nodes show decreased and increased expression of RNAs, respectively, while the colors are related to the absolute value of the fold change. Diamonds represent lncRNAs, ellipses represent miRNAs, rectangles represent mRNAs, and gray edges represent interactions among the lncRNAs-miRNAs and mRNAs. B PPI network of ceRNA network-related DEmRNAs. The nodes denote DEmRNAs (confidence score > 0.4) and the size of the nodes represents the degree of each node. C Top ten genes from the sub-network modularized by the plug-in cytoHubba. D, E Top 20 GO terms (P < 0.05) of the ceRNA-related DEmRNAs, respectively. F, G Top 20 KEGG pathways (P < 0.05) of the ceRNA-related DEmRNAs, respectively. Interactions and overlap among the important KEGG pathways. ceRNA: competing endogenous RNA;GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us