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Table 6 Multivariate analysis for Weibull AFT model

From: Application of parametric survival analysis to women patients with breast cancer at Jimma University Medical Center

Variable

Coefficient

Std. err.

z

P>|z|

ϕ

[95% conf. interval]

Age in year

>= 40

5.54

0.81

6.83

0.000*

254.06

3.95

7.13

Education

Secondary

-0.83

0.22

-3.86

0.000*

0.43

-1.26

-0.41

Degree and abo

-1.99

0.29

-6.97

0.000*

0.14

-2.55

-1.43

Residence

Urban

-0.18

00.09

-1.99

0.047*

0.84

-0.35

-0.00

Marital status

Married

0.26

0.11

2.43

0.015*

1.30

0.05

0.47

Widowed

-1.32

0.13

-9.94

0.000*

0.27

-1.58

-1.06

Divorced

0.13

0.18

0.73

0.464

1.14

-0.22

0.48

Pre-existing comorbidity

Yes

0.90

0.26

3.47

0.001*

2.46

0.39

1.41

Axillary Node status

Positive

-3.16

0.66

-4.83

0.000*

0.04

-4.45

-1.88

Estrogen receptor

Positive

-1.01

0.20

-5.01

0.000*

0.36

-1.41

-0.62

Not determine

-0.09

0.27

-0.35

0.729

0.91

-0.62

0.43

Tumor size

2–5

-0.91

0.27

-3.43

0.001*

0.40

-1.44

-0.39

> 5 cm

− 0.9496681

0.2478244

-3.83

0.000*

0.39

-1.44

-0.46

Body Mass Index at diagnosis

Overweight

2.99

0.72

4.13

0.000*

0.05

-4.41

-1.57

Progesterone receptor

Negative

-0.95

0.26

-3.66

0.000*

0.39

-1.46

-0.44

Stage of cancer

Stage II

-0.66

0.20

-3.25

0.001*

0.52

-1.05

-0.26

Stage III

-0.90

0.29

-3.15

0.002*

0.40

-1.47

-0.34

Histologic grade

Grade II

0.17

0. 0.21

0.81

0.419

1.19

-0.25 0.60

Grade III

0.16

0.22

0.75

0.455

1.17

-0.26

0.56

Number of Positive Lymph nodes involved

>=2

-0.80

0.16

-0.51

0.611

0.45

-0.40

0.23

Baseline treatment

Chemotherapy

-0.20

0.21

-0.93

0.351

0.82

-0.61

0.22

Surgery and chem.

-0.64

0.25

-2.61

0.009*

0.53

-1.12

-0.16

Type of hormone used

Anastrozole

-0.32

0.21

-1.53

0.125

0.73

-0.72

0.09

Constant

4.95

0.49

-2.97

0.000

140.55

3.96

5.89

  1. * = Significant at 5% level, P = 1.37, λ = 0.73, θ = 0.31, chi-square = 253.95, p-value = 0.000, AIC = 519.786, BIC = 646.4037