Table 3 Univariate and multivariate analysis of variables related to OS in the training cohort. (n = 732)

Age

≤ 33

Ref

Ref

34–45

2.81

1.14–6.94

0.025

4.047

1.59–10.28

0.003

Marital status

Married

Ref

Other

1.31

0.85–2.01

0.218

Race

White

Ref

Black

1.84

0.87–3.92

0.113

Other

1.39

0.89–2.17

0.150

Histology

Adenocarcinoma

Ref

Ref

Other

1.84

1.13–2.99

0.014

0.93

0.55–1.56

0.773

Tumor size(cm)

≤ 4

Ref

Ref

> 4

2.16

1.39–3.36

0.001

1.68

1.00-2.81

0.049

Grade

Grade I

Ref

Ref

Grade II

2.36

1.29–4.32

0.005

1.71

0.89–3.29

0.105

Grade III

8.75

5.07–15.08

< 0.001

3.93

1.98–7.79

< 0.001

Grade IV

22.17

10.40-47.26

< 0.001

4.64

1.82–11.87

0.001

FIGO

I

Ref

Ref

II

1.63

0.63–4.20

0.316

1.21

0.44–3.35

0.714

III

4.86

2.86–8.25

< 0.001

3.24

1.47–6.30

0.003

IV

27.40

15.97–47.97

< 0.001

13.56

5.73–32.08

< 0.001

Radiotherapy

Yes

Ref

Ref

No/Unknown

0.50

0.31–0.77

0.002

1.69

1.00-2.85

0.051

Chemotherapy

Yes

Ref

Ref

No/Unknown

0.15

0.10–0.24

< 0.001

0.91

0.45–1.85

0.793

Surgery

Yes

No

24.22

9.66–60.73

< 0.001

13.16

4.54–38.18

< 0.001