Table 2 Baseline demographic and clinicopathological characteristics with early-onset EC patients
Variables | The training cohort | The validation cohort | Total | cardinality | P |
|---|---|---|---|---|---|
No. (%) | No. (%) | No. (%) | |||
Total | 732 | 310 | 1042 | ||
Age (year) | 0.001 | 0.98 | |||
≤ 33 | 101 (13.8) | 43(13.9) | 144(13.8) | ||
33–45 | 631(86.2) | 267(86.1) | 898(86.2) | ||
Marital status | 0.09 | 0.77 | |||
Married | 354(48.4) | 153(49.4) | 507(48.7) | ||
Other | 378(51.6) | 157(50.6) | 535(51.3) | ||
Race | 5.19 | 0.07 | |||
White | 433(59.2) | 203(65.5) | 636(61.0) | ||
Black | 43(5.9) | 21(6.8) | 64(6.2) | ||
Other | 256(34.9) | 86(27.7) | 342(32.8) | ||
Histology | 0.43 | 0.51 | |||
Adenocarcinoma | 609(83.2) | 263(84.8) | 872(83.7) | ||
Other | 123(16.8) | 47(15.2) | 170(16.3) | ||
Tumor size(cm) | 0.58 | 0.45 | |||
≤ 4 | 392(53.6) | 174(56.1) | 566(54.3) | ||
> 4 | 340(46.4) | 136(43.9) | 476(45.7) | ||
Grade | 0.43 | 0.93 | |||
Grade I | 428(58.5) | 184(59.4) | 612(58.7) | ||
Grade II | 191(26.1) | 83(26.8) | 274(26.3) | ||
Grade III | 95(13.0) | 36(11.6) | 131(12.6) | ||
Grade IV | 18(2.4) | 7(2.2) | 25(2.4) | ||
FIGO | 0.49 | 0.92 | |||
I | 528(72.1) | 230(77.1) | 758(72.7) | ||
II | 57(7.8) | 23(7.4) | 80(7.7) | ||
III | 111(15.2) | 43(13.9) | 154(14.8) | ||
IV | 36(4.9) | 14(4.5) | 50(4.8) | ||
Radiotherapy | 0.39 | 0.53 | |||
Yes | 164(22.4) | 75(24.2) | 239(22.9) | ||
No/Unknown | 568(77.6) | 235(75.8) | 803(77.1) | ||
Chemotherapy | 2.09 | 0.15 | |||
Yes | 141(19.3) | 48(15.5) | 189(18.1) | ||
No/Unknown | 591(80.7) | 262(84.5) | 853(81.9) | ||
Surgery | 1.00 | 0.67 | |||
Yes | 725(99.0) | 308(99.4) | 1033(99.1) | ||
No | 7(1.0) | 2(0.6) | 9(0.9) |