Period | No. patients (N) | Mean (SD) | Lower bound | Upper bound | Normality (Shapiro–Wilk, W) | |
---|---|---|---|---|---|---|
Future uncertainty | Baseline | 52 | 1.8 (0.7) | 1.6 | 2.1 | 0.87 |
Day 7 | 49 | 1.7 (0.6) | 1.5 | 1.8 | 0.86 | |
Day 30 | 46 | 1.5 (0.6) | 1.4 | 1.7 | 0.81 | |
Day 90 | 28 | 1.5 (0.7) | 1.3 | 1.8 | 0.79 | |
Day 180 | 20 | 1.7 (0.6) | 1.4 | 2.0 | 0.90 | |
Visual disorder | Baseline | 52 | 1.6 (0.7) | 1.4 | 1.8 | 0.79 |
Day 7 | 49 | 1.5 (0.5) | 1.3 | 1.6 | 0.82 | |
Day 30 | 46 | 1.5 (0.6) | 1.3 | 1.7 | 0.79 | |
Day 90 | 28 | 1.3 (0.4) | 1.1 | 1.5 | 0.72 | |
Day 180 | 20 | 1.4 (0.5) | 1.1 | 1.6 | 0.76 | |
Motor dysfunction | Baseline | 52 | 1.9 (0.8) | 1.7 | 2.2 | 0.89 |
Day 7 | 49 | 1.8 (0.7) | 1.6 | 2.1 | 0.92 | |
Day 30 | 46 | 1.8 (0.7) | 1.6 | 2.0 | 0.91 | |
Day 90 | 28 | 1.5 (0.4) | 1.4 | 1.7 | 0.80 | |
Day 180 | 20 | 1.6 (0.5) | 1.3 | 1.8 | 0.90 | |
Communication deficit | Baseline | 52 | 1.5 (0.8) | 1.3 | 1.7 | 0.68 |
Day 7 | 49 | 1.3 (0.5) | 1.1 | 1.5 | 0.63 | |
Day 30 | 46 | 1.3 (0.6) | 1.1 | 1.4 | 0.52 | |
Day 90 | 28 | 1.2 (0.4) | 1.0 | 1.3 | 0.51 | |
Day 180 | 20 | 1.1 (0.2) | 1.0 | 1.1 | 0.45 | |
Headache | Baseline | 52 | 2.4 (1.1) | 2.5 | 2.8 | 0.85 |
Day 7 | 49 | 1.7 (0.8) | 1.4 | 1.9 | 0.77 | |
Day 30 | 46 | 1.4 (0.6) | 1.2 | 1.5 | 0.64 | |
Day 90 | 28 | 1.2 (0.4) | 1.0 | 1.3 | 0.47 | |
Day 180 | 20 | 1.4 (0.6) | 1.1 | 1.6 | 0.63 | |
Seizures | Baseline | 52 | 1.4 (0.7) | 1.2 | 1.6 | 0.58 |
Day 7 | 49 | 1.2 (0.5) | 1.1 | 1.4 | 0.52 | |
Day 30 | 46 | 1.3 (0.7) | 1.5 | 1.5 | 0.53 | |
Day 90 | 28 | 1.1 (0.3) | 1.0 | 1.2 | 0.29 | |
Day 180 | 20 | 1.1 (0.3) | 1.0 | 1.2 | 0.35 | |
Drowsiness | Baseline | 52 | 1.6 (0.8) | 1.3 | 1.8 | 0.70 |
Day 7 | 49 | 1.5 (0.6) | 1.3 | 1.6 | 0.69 | |
Day 30 | 46 | 1.4 (0.7) | 1.1 | 1.6 | 0.58 | |
Day 90 | 28 | 1.2 (0.5) | 1.0 | 1.4 | 0.54 | |
Day 180 | 20 | 1.2 (0.4) | 1.0 | 1.3 | 0.43 | |
Hair loss | Baseline | 52 | 1.1 (0.4) | 1.0 | 1.2 | 0.34 |
Day 7 | 49 | 1.2 (0.6) | 1.0 | 1.3 | 0.34 | |
Day 30 | 46 | 1.2 (0.5) | 1.0 | 1.3 | 0.36 | |
Day 90 | 28 | 1.1 (0.3) | 1.0 | 1.2 | 0.29 | |
Day 180 | 20 | 1.0 (0.0) | 1.0 | 1.0 | - | |
Itchy skin | Baseline | 52 | 1.1 (0.3) | 1.0 | 1.2 | 0.40 |
Day 7 | 49 | 1.1 (0.4) | 1.0 | 1.3 | 0.31 | |
Day 30 | 46 | 1.1 (0.4) | 1.0 | 1.2 | 0.32 | |
Day 90 | 28 | 1.0 (0.2) | 1.0 | 1.1 | 0.19 | |
Day 180 | 20 | 1.1 (0.2) | 1.0 | 1.2 | 0.24 | |
Weakness of both legs | Baseline | 52 | 1.9 (0.9) | 1.6 | 2.1 | 0.78 |
Day 7 | 49 | 1.8 (1.0) | 1.6 | 2.1 | 0.78 | |
Day 30 | 46 | 1.7 (0.9) | 1.5 | 2.0 | 0.76 | |
Day 90 | 28 | 1.3 (0.5) | 1.1 | 1.5 | 0.59 | |
Day 180 | 20 | 1.3 (0.4) | 1.0 | 1.5 | 0.54 | |
Bladder control | Baseline | 52 | 1.8 (0.9) | 1.6 | 2.1 | 0.78 |
Day 7 | 49 | 0.6 (0.8) | 1.4 | 1.8 | 0.71 | |
Day 30 | 46 | 1.4 (0.8) | 1.2 | 1.7 | 0.63 | |
Day 90 | 28 | 1.3 (0.5) | 1.1 | 1.5 | 0.58 | |
Day 180 | 20 | 1.3 (0.6) | 1.0 | 1.5 | 0.52 |