Table 2 Health-related quality of life measured by EQ-5D-5L utility scores by tumor stages
EQ-5D Domain | Health State | Stage-0 | Stage-I | Stage-II | Stage-III | Stage-IV | Overall | p-value |
|---|---|---|---|---|---|---|---|---|
Mobility | No problems | 13 (65.00) | 137 (53.94) | 101 (50.75) | 61 (59.80) | 18 (56.25) | 330 (54.37) | 0.010 |
Slight problems | 3 (15.00) | 65 (25.59) | 56 (28.14) | 17 (16.67) | na | 141 (23.23) | ||
Moderate problems | 4 (20.00) | 22 (8.66) | 24 (12.06) | 16 (15.69) | 6 (18.75) | 72 (11.86) | ||
Severe problems | na | 17 (6.69) | 14 (7.04) | 5 (4.90) | 5 (15.63) | 41 (6.75) | ||
Unable/extreme problems | na | 13 (5.12) | 4 (2.01) | 3 (2.94) | 3 (9.38) | 23 (3.79) | ||
Self-care | No problems | 13 (65.00) | 126 (49.61) | 85 (42.71) | 57 (55.88) | 15 (46.88) | 296 (48.76) | |
Slight problems | 5 (25.00) | 72 (28.35) | 57 (28.64) | 22 (21.57) | 1 (3.13) | 157 (25.86) | 0.007 | |
Moderate problems | na | 36 (14.17) | 37 (18.59) | 12 (11.76) | 7 (21.88) | 92 (15.16) | ||
Severe problems | 2 (10.00) | 12 (4.72) | 15 (7.54) | 7 (6.86) | 5 (15.63) | 41 (6.75) | ||
Unable/extreme problems | na | 8 (3.15) | 5 (2.51) | 4 (3.92) | 4 (12.50) | 21 (3.46) | ||
Usual activities | No problems | 11 (55.00) | 96 (37.80) | 62 (31.16) | 45 (44.12) | 14 (43.75) | 228 (37.56) | |
Slight problems | 3 (15.00) | 73 (28.74) | 59 (29.65) | 23 (22.55) | 2 (6.25) | 160 (26.36) | 0.002 | |
Moderate problems | 2 (10.00) | 43 (16.93) | 39 (19.60) | 18 (17.65) | 5 (15.63) | 107 (17.63) | ||
Severe problems | 4 (20.00) | 31 (12.20) | 23 (11.56) | 7 (6.86) | 3 (9.38) | 68 (11.20) | ||
Unable/extreme problems | na | 11 (4.33) | 16 (8.04) | 9 (8.82) | 8 (25.00) | 44 (7.25) | ||
Pain/discomfort | No problems | 4 (20.00) | 39 (15.35) | 44 (22.11) | 22 (21.57) | 4 (12.50) | 113 (18.62) | 0.021 |
Slight problems | 5 (25.00) | 74 (29.13) | 73 (36.68) | 38 (37.25) | 8 (25.00) | 198 (32.62) | ||
Moderate problems | 9 (45.00) | 76 (29.92) | 44 (22.11) | 33 (32.35) | 9 (28.13) | 171 (28.17) | ||
Severe problems | 2 (10.00) | 50 (19.69) | 26 (13.07) | 7 (6.86) | 7 (21.88) | 92 (15.16) | ||
Unable/extreme problems | na | 15 (5.91) | 12 (6.03) | 2 (1.96) | 4 (12.50) | 33 (5.44) | ||
Anxiety/depression | No problems | 2 (10.00) | 9 (3.54) | 4 (2.01) | 2 (1.96) | 1 (3.13) | 18 (2.97) | |
Slight problems | 5 (25.00) | 47 (18.50) | 26 (13.07) | 12 (11.76) | 3 (9.38) | 93 (15.32) | 0.207 | |
Moderate problems | 8 (40.00) | 92 (36.22) | 73 (36.68) | 35 (34.31) | 10 (31.25) | 218 (35.91) | ||
Severe problems | 4 (20.00) | 62 (24.41) | 55 (27.64) | 35 (34.31) | 7 (21.88) | 163 (26.85) | ||
Unable/extreme problems | 1 (5.00) | 44 (17.32) | 41 (20.60) | 18 (17.65) | 11 (34.38) | 115 (18.95) |