Fig. 8

ERK inhibitor PD98059 attenuates CXCL3-induced malignant behaviors in COAD cells. (A-B) CCK-8 analysis for COAD cells treatment with DMSO (Control) and 100 µΜ PD98059. (C-D) The inhibition rate analyses of cell proliferation derived from PD98059 on CXCL3-overexpressing COAD cells and their mock control cells. (E-F) Representative images of transwell analysis for COAD cells treatment with DMSO (Control) and 100 µΜ PD98059. (G-H) transwell analysis for COAD cells treatment with DMSO (Control) and 100 µΜ PD98059. (I-J) The inhibition rate analyses of cell migration derived from PD98059 on CXCL3-overexpressing COAD cells and their mock control cells. ^**P < 0.01 vs. DMSO, ^##P < 0.01 vs. MOCK, ^#P < 0.05 vs. MOCK.