Fig. 7
From: Prognostic marker CXCL5 in glioblastoma polyformis and its mechanism of immune invasion
CXCL5 promotes GBM cell progression by inhibiting macrophage and Th1 immune infiltration. A Immunofluorescence showing expression of macrophage marker CD68 in mouse brain tissue after CXCL5 inhibition (statistical values are shown in C); B Mouse normal brain tissue under various treatments. The expression of CXCL5 in transplanted tumors (statistical values are shown in D); E RT-qPCR showing the expression of CXCL5, CD68, MARCO, and IFN-γR1;Subcutaneous tumor was injected into cells of each group to construct a mouse subcutaneous tumor model, and the subcutaneous tumor weight of each group was weighed (F) and the results of the mouse survival cycle of each group were analyzed after the third week (G). Asterisks *, **, and *** represent p < 0.05, p < 0.01, and p < 0.001, respectively