Table 3 The Cox regression analysis among clinical traits and OS in validation set

Gender

0.489

 Male

47

Reference

 Female

43

0.835 (0.500–1.394)

0.490

Age

90

1.006 (0.978–1.036)

0.663

Smoking history

0.527

 Non-smoker

50

Reference

 Smoker

40

1.181 (0.707–1.972)

0.526

ECOG-PS

0.134

 0

35

Reference

 1

55

1.499 (0.874–2.572)

0.142

TNM stage

< 0.001

 I

41

Reference

Reference

 II

8

3.840 (1.590–9.275)

0.003

3.265 (0.656–16.256)

0.149

 III

41

3.308 (1.867–5.864)

< 0.001

2.618 (0.634–10.801)

0.183

T stage

0.017

 <3 cm

50

Reference

Reference

 ≥ 3 cm

40

1.877 (1.121–3.143)

0.017

1.149 (0.646–2.043)

0.637

 N stage

< 0.001

 Negative

43

Reference

Reference

 Positive

47

3.122 (1.814–5.374)

< 0.001

0.888 (0.227–3.474)

0.864

IHC score of SFXN1

90

1.253 (1.121–1.402)

< 0.001

1.178 (1.032–1.345)

0.016