Fig. 5

Genetic variations of SFXN1 in LUAD from TCGA database. A-B Mutation frequencies of high (A) and low (B) expression group of SFXN1 in 243 LUAD patients according to the TCGA dataset. Each column represents one patient, the bar on the top represents the TMB, and the numbers on the right mean the mutation frequency of the top 20 common genes in the corresponding group. C-D Enriched pathways of SFXN1 mutation in high (C) and low (D) expression groups. E TMB difference between SFXN1 low and high group. F Correlation of TMB with the prognostic risk score in LUAD patients