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Table 6 mRNA correlation between LAG3 and gene markers of TIICs in MPM from TCGA with a multivariate linear regression model

From: LAG3 is an independent prognostic biomarker and potential target for immune checkpoint inhibitors in malignant pleural mesothelioma: a retrospective study

Gene markers

β

95% CI

P value

CD274

0.0839

-0.0753–0.2433

0.2978

PDCD1

0.4915

0.1926–0.7905

0.0016

CTLA4

-0.1120

-0.4940–0.2700

0.5611

CD80

0.2795

-0.0476–0.6068

0.0930

CD38

0.3021

0.0889–0.5152

0.0061

CD8A

-0.3154

-0.8362–0.2054

0.2316

CD8B

0.2144

-0.2179–0.6466

0.3265

ICOS

0.0611

-0.3994–0.5215

0.7924

  1. TIICs Tumor immune infiltration cells, MPM Malignant pleural mesothelioma, TCGA The Cancer Genome Atlas, β Regression coefficient