Table 4 Multivariate Cox proportion hazards model for OS showing elevated LAG3 immunohistochemical expression as an independent prognostic biomarker in MPM

Covariate

HR

95% CI

P value

HR

95% CI

P value

Age

1.0176

0.9887–1.048

0.2374

1.0099

0.9480–1.07776

0.7616

Male/Female

0.8837

0.4837–1.6143

0.6909

0.2613

0.0812–0.8409

0.0351

Stage

 II vs. I

0.5766

0.2357–1.4105

0.2277

0.8769

0.2192–3.5076

0.8527

 III vs. I

0.6688

0.3061–1.4612

0.3131

4.2209

1.0627–16.7644

0.0407

 IV vs. I

0.6920

0.2855–1.6772

0.4150

14.1624

2.3848–84.1033

0.0035

LAG3

0.8779

0.7643–1.0050

0.0592

0.2255

0.0610–0.8337

0.0197