Table 1 LAG3 association with prognosis of multiple cancers in TCGA database

Cancer type

N

Biomarker

Poor prognosis

P value

Kidney clear cell carcinoma

606

mRNA

OS

< 0.0001

604

mRNA

PFS

0.0433

Kidney papillary cell carcinoma

321

mRNA

PFS

0.0293

Lower-grade glioma

528

mRNA

OS

0.0302

Ocular melanomas

80

mRNA

OS

< 0.0001

79

mRNA

PFS

0.0056

Pan-cancer

10952

mRNA

OS

0.0138

Lower-grade glioma and glioblastoma

694

mRNA

OS

< 0.0001

694

mRNA

PFS

< 0.0001

Cancer type

N

Biomarker

Better prognosis

P value

Bladder cancer

426

mRNA

PFS

0.0307

Liver cancer

422

mRNA

PFS

0.0049

Melanoma

458

mRNA

OS

< 0.0001

459

mRNA

PFS

0.0049

Thyroid cancer

572

mRNA

OS

0.0149