Table 3 The relationships between radiological characteristics and GLS1 expression level
Ce-MRI characteristics | n = 120 | GLS1 | P value | |
|---|---|---|---|---|
Negative (-/+, n = 89) | Positive (++/+++, n = 31) | |||
Serum AFP (ng/ml) | 20.85 (2.93−131.58) | 14.00 (2.85−115.55) | 52.40 (3.40−226.50) | 0.118 |
Dimension (cm) | 3.35 (2.20–5.17) | 3.40 (2.45–5.10) | 2.80 (2.00−5.60) | 0.549 |
Tumor in vein (+) | 5 (4.2) | 3 (3.4) | 2 (6.5) | 0.603 |
Shape | 0.053 | |||
Round | 85 (70.8) | 68 (76.4) | 17 (54.8) | |
Lobular | 9 (7.5) | 5 (5.6) | 4 (12.9) | |
Irregular | 26 (21.7) | 16 (18.0) | 10 (32.3) | |
Nonrim APHE (+) | 92 (76.7) | 74 (83.1) | 18 (58.1) | 0.004 |
Nonrim APHE (-) | 28 (23.3) | 15 (16.9) | 13 (41.9) | |
Nonperipheral washout (+) | 95 (79.2) | 75 (84.3) | 20 (64.5) | 0.020 |
Nonperipheral washout (-) | 25 (20.8) | 14 (15.7) | 11 (35.5) | |
Enhancing capsule (+) | 19 (15.8) | 15 (16.9) | 4 (12.9) | 0.778 |
Blood in mass (+) | 12 (10) | 8 (9) | 4 (12.9) | 0.532 |
Fat in mass (+) | 51 (42.5) | 40 (44.9) | 11 (35.5) | 0.359 |
Necrosis (+) | 11 (9.2) | 8 (9.0) | 3 (9.7) | 0.909 |
Maxium ADC (×10 − 6 mm2 /s) | 1031 (868–1255) | 1076 (874–1255) | 974 (862–1281) | 0.299 |
Minium ADC (×10 − 6 mm2 /s) | 651 (516–790) | 663 (542–832) | 622 (463–737) | 0.150 |
Median ADC (×10 − 6 mm2 /s) | 817 (713–993) | 835 (714–1013) | 785 (641–890) | 0.184 |
Liver ADC (×10 − 6 mm2 /s) | 1022 (919–1054) | 1012 (935–1153) | 1055 (894–1163) | 0.129 |
Lesion-to-liver ADC ratio | 0.821 (0.702–0.935) | 0.837 (0.717–0.951) | 0.783 (0.678–0.875) | 0.074 |
Satellite nodules (+) | 28 (23.5) | 21 (23.9) | 7 (22.6) | 0.885 |
Liver background | 0.243 | |||
Fat | 38 (31.7) | 31 (34.8) | 7 (22.6) | |
Iron | 12 (10.0) | 7 (7.9) | 5 (16.1) | |
LIRADS v2018 category | 0.026 | |||
LIRADS−3 | 18 (15.0) | 9 (10.1) | 9 (29.0) | |
LIRADS−4 | 32 (26.7) | 23 (25.8) | 9 (29.0) | |
LIRADS−5 | 70 (58.3) | 57 (64.0) | 13 (41.9) | |
Lesion-to-liver ratio (AP) | 1.231 (0.987–1.580) | 1.301 (1.010–1.627) | 1.108 (0.850–1.352) | 0.038 |
Lesion-to-liver ratio (PP) | 0.847 (0.699–0.930) | 0.857 (0.735–0.954) | 0.752 (0.611–0.884) | 0.040 |
Lesion-to-liver ratio (DP) | 0.733 (0.620–0.833) | 0.774 (0.662–0.852) | 0.654 (0.549–0.738) | 0.002 |
Lesion-to-liver ratio (HBP) | 0.530 (0.423–0.659) | 0.568 (0.456–0.683) | 0.423 (0.369–0.493) | < 0.001 |
Lesion-to-liver ratio in uncontrast-enhanced T1 | 0.764 (0.658–0.898) | 0.776 (0.658–0.904) | 0.714 (0.660–0.885) | 0.528 |
Lesion-to-liver ratio (T2) | 2.096 (1.707–2.591) | 2.096 (1.741–2.591) | 1.976 (1.654–2.639) | 0.735 |
Eligible observations | 32 | 16 | 16 | Â |
SUVmax | 3.75 (2.90–6.90) | 3.35 (2.80–5.23) | 5.15 (3.10–8.40) | 0.080 |