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Fig. 2 | BMC Cancer

Fig. 2

From: Identification and validation of a ferroptosis-related signature for prediction of the prognosis and tumor microenvironment in patients with chromophobe renal cell carcinoma

Fig. 2

Genetic mutation and differential expression of FRGs in ChRCC. A Mutations frequencies of 60 FRGs in 66 ChRCC patients from TCGA. B Frequencies of CNV gain, loss, and non-CNV of FRGs. C Locations of CNV changes in FRGs on chromosomes. D Interaction network among FRGs in ChRCC. The thickness of the connection line indicates the strength of the interaction between genes. Heatmap (E) and volcano plots (F) for expression of differentially expressed FRGs in tumor and normal tissues. Red and blue represent upregulation and downregulation of genes, respectively. The PPI network (G) and correlation (H) between differentially expressed FRGs.

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