Fig. 4

CAFs can remodel BC tumor microenvironment. A XCell algorithm was used to quantify the BC microenvironment; B The quantified immune and stromal cells in patients with high and low CAFs infiltration; C Quantified immune function in patients with high and low CAFs infiltration; D Correlation between CAFs and endothelial cells; E Correlation between CAFs and M2 macrophages; F Correlation between M2 macrophages and endothelial cells; G Correlation of CAFs, M2 macrophages, endothelial cells with EMP1, ACKR3, ITGA10, MMP13, COL11A1, and THY1; H Expression pattern of immune-related genes in BC samples; I The immune-related genes in patients with high and low CAFs infiltration; J: Pathway enrichment analysis