Table 1 Other circRNA-miRNA-mRNA axes and affected signaling pathway and cancer stemness reported for the circZNF800-regulated circRNAs and mRNAs
Cancer | circRNA/miRNA /mRNAa | Signaling pathway affected | Cancer stem cell-associated properties | Reference |
|---|---|---|---|---|
A. circZNF800-modulated miRNA group | ||||
 Lung adenocarcinoma | miR-140-3p | WNT/β-catenin | Chemosensitivity | [53] |
 Glioma | CircUBAP2 / miR-382-5p / GPRC5A | NA | Cell proliferation, migration & invasion | [44] |
 Osteosarcoma | miR-382-5p / YB-1 | NA | Metastasis & relapse | [47] |
 Pancreatic | miR-382-5p / ANXA3 | PI3K/AKT | Tumor progression | [45] |
 Colorectal | miR-382-5p / KLF12 & HIPK3 | NA | Cell proliferation, migration, invasion & chemosensitivity | [46] |
 Glioblastoma multiform | miR-579-3p / AKT1 | PI3K/AKT | Cell proliferation & migration | [54] |
B. circZNF800-modulate mRNA group | ||||
 Prolactinoma | ALK7 | Activin | Cell proliferation | [55] |
 Retinoblastoma | ALK7 | ALK7/SMAD2 | Cell proliferation & invasion | [56] |
 CML | circCBFB / miR-607 / FZD3 | WNT/β-catenin | Cell proliferation | [57] |
 Gastric | WNT5A | NA | Cell migration &invasion | [49] |
 Erb2-induced breast cancer | WNT5A | TGFβ-SMAD | Expansion of tumor-initiating cells | [48] |
 NPC | WNT5A | Promoted EMT | Increased CD24-CD44 + cells & metastasis | [51] |
 NSCLC | CircVAPA / miR-876-5p / WNT5A | WNT/β-catenin | Cell proliferation, migration, invasion and stemness | [50] |
 Bladder | miR-374a / WNT5A | NA | Metastasis and invasiveness | [52] |