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Table 1 Patient characteristics (n 45)

From: The role of spleen volume change in predicting immunotherapy response in metastatic renal cell carcinoma

  

Splenic Volume

 

Group

Total n %

Not increased

İncreased

P

Age

    < 65 years

29 (64)

16 (69.6)

13 (59.1)

0.46

    ≥ 65 years

16 (36)

7 (30.4)

9 (40.9)

 

Gender

    Female

14 (31)

13 (56.5)

19 (86.4)

0.02

    Male

31 (69)

10 (43.5)

3 (13.6)

 

ECOG performance status

    0–1

34 (76)

18 (78.3)

16 (72.7)

0.66

    ≥ 2

11 (24)

5 (21.7)

6 (27.3)

 

Nephrectomy

    Yes

33 (73)

4 (17.4)

8 (86.4)

0.15

    No

12 (27)

19 (82.6)

14 (13.6)

 

IMDC Risk Group

    Favorable

7 (16)

3 (13)

3 (13.6)

0.49

    Intermediate

36 (80)

20 (87)

17 (77.3)

 

    Poor

2 (4)

0 (0)

2 (9.1)

 

Tumor Histology

    Clear Cell

39 (87)

19 (82.6)

20 (90.9)

0.66

    Non-clear Cell

6 (13)

4 (17.4)

2 (9.1)

 

Body Mass Index Status (kg/ m2)

    < 25

22 (49)

9 (39.1)

13 (59.1)

0.42

    25-29.9

14 (31)

9 (39.1)

5 (22.7)

 

    ≥ 30

9 (20)

5 (21.7)

4 (18.2)

 

Number of prior systemic therapies

    1

21 (47)

9 (39.1)

13 (59.1)

0.18

    2

24 (53)

14 (60.9)

9 (40.9)

 

Sites of metastases at baseline

    

    Lung

24

14

10

 

    Liver

7

2

4

 

    Bone

14

8

5

 

    Lymph node

12

7

6

 

    Brain

1

0

1

 

    Others

4

2

2