Dietary advanced glycation end products are associated with an increased risk of breast cancer in Iranian adults

BMC Cancer

Table 3 Odds ratios (ORs) and 95% confidence intervals (CIs) for breast cancer based on tertiles of dietary advanced glycation end products (AGEs)

	Tertiles of dietary advanced glycation end products
	T1	T2	T3	P for trend
Median score of dietary AGEs	6594	9125	13,628
Case/Total	36 / 125	53 / 143	44 / 133
Model 1^*	1.00 (Ref)	1.47 (0.87–2.46)	1.22 (0.71–2.07)	0.459
Model 2^†	1.00 (Ref)	1.77 (1.03–3.06)	2.29 (1.19–4.39)	0.012
Model 3^‡	1.00 (Ref)	1.61 (0.92–2.81)	2.16 (1.11–4.18)	0.023
Model 4^¶	1.00 (Ref)	1.62 (0.92–2.85)	2.33 (1.18–4.60)	0.017

^*Model 1: Crud model
^†Model 2: Adjusted for age, first pregnancy age, and energy intake
^‡ Model3: adjusted for model 2 and menopausal status, family history of cancer, anti-inflammatory drug use, Vitamin D supplementation, physical activity
^¶ Model 4: adjusted for model 3 and BMI, number of childbirths, and history of abortion, breastfeeding, and OCP use

ISSN: 1471-2407