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Fig. 4 | BMC Cancer

Fig. 4

From: LRPPRC regulates malignant behaviors, protects mitochondrial homeostasis, mitochondrial function in osteosarcoma and derived cancer stem-like cells

Fig. 4

LRPPRC regulates FOXM1 and its downstream genes. (A) After LRPPRC knockdown, western blot was performed to detect FOXM1 and its downstream genes, including PRDX3, MnSOD and Catalase in MG63, U2OS and there CSCs. (B) After 24-h culture in normoxia or hypoxia, ROS level were measured MG63, U2OS or their CSCs. *P<0.05, vs. shScram group; #P<0.05, vs. shLRPPRC group

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