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Fig. 3 | BMC Cancer

Fig. 3

From: LRPPRC regulates malignant behaviors, protects mitochondrial homeostasis, mitochondrial function in osteosarcoma and derived cancer stem-like cells

Fig. 3

LRPPRC knockdown inhibited stemness in osteosarcoma parental cells and derived CSCs. (A) MG63 and U2OS parental cells with LRPPRC knockdown presented decreased sphere formation capacities. (B) LRPPRC is efficiently knockdown in CSCs derived from MG63 or U2OS cells. (C) CSCs derived from MG63 or U2OS cells with knockdown LRPPRC presented decreased sphere formation capacities. After LRPPRC knockdown, invasion and tumor formation in soft agar were measured (D&E).

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BMC Cancer

ISSN: 1471-2407

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