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Table 1 Correlation of clinicopathological and demographic parameters of CRC patients with PD-L1 and PD-L2 expression

From: Cholinergic signaling influences the expression of immune checkpoint inhibitors, PD-L1 and PD-L2, and tumor hallmarks in human colorectal cancer tissues and cell lines

Parameters

No. of cases

Percentage (%)

PD-L1 expression

Low High

P values

Total

91

100

38 (41.8%)

53 (58.2%)

 

Gender

Male

Female

51

40

56.0

44.0

21 (23.1%)

17 (18.7%)

30 (30.0%)

23 (25.3%)

0.534

Age

<65

>65

41

50

45.1

54.9

17 (18.7%)

21 (23.1%)

24 (26.0%)

29 (31.9%)

0.565

Stage

I + II

III + IV

49

42

53.8

46.2

29 (31.9%)

9 (9.9%)

20 (22.0%)

33 (36.3%)

0.0001

Parameters

No. of cases

Percentage (%)

PD-L2 expression

Low High

Pvalues

Total

91

100

69 (75.8%)

22 (24.2%)

 

Gender

Male

Female

51

40

56.0

44.0

39 (42.9%)

30 (33.0%)

12 (13.2%)

10 (11.0%)

0.531

Age

<65

>65

41

50

45.1

54.9

31 (34.1%)

38 (41.8%)

10 (11.0%)

12 (13.2%)

0.579

Stage

I + II

III + IV

49

42

53.8

46.2

37 (40.7%)

32 (35.9%)

12 (13.2%)

10 (11.0%)

0.569

  1. P values are based on the frequency of PD-L1 and PD-L2 expression within each parameter