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Table 2 Patient characteristics according to IDH mutation. Median age was comparable in mutated and wild-type groups. The IDH mutation rate was not different in localized (43%) vs. metastatic (50%) patients; while it was significantly higher in G3 (69%) than in G2 (37%) tumors (p=0.0390)

From: IDH mutations in G2-3 conventional central bone chondrosarcoma: a mono institutional experience

 

all

sample = 54

IDHmut

N = 24

IDHwt

N = 30

P value

Age, median(range)

63 (17–85)

60 (33–85)

64 (17–79)

0.2889

Site, n (%)

    

Extremity

25 (46%)

14 (56%)

11 (44%)

0.2357

Pelvis

18 (33%)

7 (39%)

11 (61%)

 

Other

11 (21%)

3 (27%)

8 (73%)

 

Grade, n (%)

    

G2

41 (76%)

15 (37%)

26 (63%)

0.0390

G3

13 (24%)

9 (69%)

4 (31%)

 

Stage, n (%)

    

Localized

40 (74%)

17 (43%)

23 (57%)

0.6269

Metastatic

14 (26%)

7 (50%)

7 (50%)

 

Margins, n (%)

    

Wide

39 (75%)

17 (44%)

22 (56%)

0.5206

Not-wide

13 (25%)

7 (54%)

6 (46%)

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