Table 1 Changes in exerkines in CC
Changes in cachexia | Exerkines | Increase | Decrease | not clear |
|---|---|---|---|---|
Skeletal muscle | Myokines | |||
Myostatin | ✓ | |||
Follistatin | ✓ | |||
irisin | ✓ | |||
IL-6 | ✓ | |||
FGF-21 | ✓ | |||
Myonectin | ✓ | |||
Adipose tissue | Adipokines | |||
Leptin | ✓ | |||
Adiponectin | ✓ | |||
Resistin | ✓ | |||
Chemerin | ✓ | |||
Visfatin | ✓ | |||
Omentin | ✓ | |||
Vaspin | ✓ | |||
Progranulin | ✓ | |||
Heart | Cardiokines | |||
ANP | ✓ | |||
BNP | ✓ | |||
IL-33 | ✓ | |||
IL-18 | ✓ | |||
IL-6 | ✓ | |||
IL-1β | ✓ | |||
Follistatin | ✓ | |||
TGF-β | ✓ | |||
Ang-II | ✓ | |||
TNF-α | ✓ | |||
Liver | Hepatokines | |||
Activin-E | ✓ | |||
ANGPTL-4 | ✓ | |||
FGF-21 | ✓ | |||
Follistatin | ✓ |