The risk of acute kidney injury in colorectal cancer survivors: an english population-based matched cohort study

BMC Cancer

Table 2 Adjusted Hazard ratios (HR) and stratum-specific HRs of incident AKI in individuals with a prior diagnosis of colorectal compared to matched individuals with no history of cancer, by exposure to resectional surgery for colorectal cancer and time since index date. HRs were calculated using Cox proportional hazards stratified by matched set with time since index date as the underlying timescale

			95% CI
	Category	Hazard Ratio^a	Lower	Upper
Fully adjusted model	colorectal cancer surgery	1.93	1.82	2.05
Fully adjusted model	colorectal cancer no surgery	2.86	2.60	3.13
Time since index		Stratum-specific HR^a
0–1 years	colorectal cancer surgery	7.87	6.78	9.13
0–1 years	colorectal cancer no surgery	6.89	5.76	8.25
1 year	colorectal cancer surgery	2.16	1.77	2.64
1 year	colorectal cancer no surgery	3.58	2.79	4.60
2 years	colorectal cancer surgery	1.86	1.53	2.26
2 years	colorectal cancer no surgery	3.57	2.64	4.82
3 years	colorectal cancer surgery	1.69	1.38	2.06
3 years	colorectal cancer no surgery	2.63	1.88	3.66
4 years	colorectal cancer surgery	1.47	1.18	1.83
4 years	colorectal cancer no surgery	1.93	1.35	2.75
5 or more years	colorectal cancer surgery	1.25	1.15	1.37
5 or more years	colorectal cancer no surgery	1.31	1.10	1.54

^aAdjusted for age, sex, GP practice, social deprivation, BMI category, smoking status, problem drinking, diabetes, cardiovascular disease, hypertension, autoimmune disease, rheumatoid arthritis, and chronic kidney disease

ISSN: 1471-2407