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Table 3 Summary of trial characteristics by tumour site

From: Clinical trials in cancer screening, prevention and early diagnosis (SPED): a systematic mapping review

Tumour Type

 

Colorectal

Upper gastrointestinal/ hepatobiliary

Urology

Breast

Gynaecological

Head and neck

Lung

Multiple

Skin

Number (N = 744)

%

Number (N = 174)

%

Number (N = 214)

%

Number (N = 283)

%

Number (N = 399)

%

Number (N = 36)

%

Number (N = 146)

%

Number (N = 111)

%

Number (N = 152)

%

Intervention

Endoscopy (242)

33

Endoscopy (53)

30

Pharmacological (50)

23

Health promotion (107)

38

Diagnostic test (88)

22

Imaging (10)

28

Imaging (62)

42

Health promotion (50)

45

Health promotion (63)

41

Health promotion (206)

28

Imaging (40)

23

Imaging (42)

20

Imaging (74)

26

Pharmacological (79)

20

Diagnostic test (9)

25

Health promotion (24)

16

Pharmacological (28)

25

Pharmacological (35)

23

 

Pharmacological (83)

Behaviour change (50)

Imaging (43)

Molecular test (29)

Biomarkers (15)

Questionnaire (12)

Standard of care (9)

11

7

6

4

2

2

1

Diagnostic test (27)

Pharmacological (20)

Health promotion (14)

Biomarker (10)

Surgery (5)

16

12

8

6

3

Diagnostic test (32)

Health promotion (29)

Biomarker (14)

Standard of care (11)

Molecular test (11)

Behaviour change (8)

Prediction tool (6)

15

14

7

5

5

4

3

Pharmacological (41)

Behaviour change (30)

Lifestyle (8)

Diagnostic test (7)

Standard of care (4)

14

11

3

2

1

Health promotion (79)

Molecular test (53)

Standard of care (24)

Imaging (12)

Biomarker (11)

Endoscopy (10)

Questionnaire (8)

Prediction tool (5)

20

13

6

3

3

3

2

1

Pharmacological (6)

Biomarker (4)

Endoscopy (2)

Behaviour change (2)

17

11

6

6

Pharmacological (17)

Behaviour change (10)

Biomarker (9)

Endoscopy (8)

Diagnostic test (7)

Questionnaire (4)

Risk prediction (2)

12

7

6

5

5

3

1

Behaviour change (8)

Lifestyle (6)

Questionnaire (4)

Imaging (4)

Diagnostic test (3)

Risk prediction (2)

75

4

4

3

2

Behaviour change (24)

Diagnostic test (9)

Imaging (7)

Questionnaire (7)

Light therapy (3)

16

6

5

5

2

Geographical area (top 3)

North America (298)

40

Asia (70)

40

Europe (87)

41

North America (138)

49

Europe (127)

32

Asia (17)

47

Europe (62)

43

North America (66)

59

North America (87)

57

Europe (260)

35

Europe (45)

26

North America (86)

40

Europe (70)

25

North America (117)

29

Europe (9)

25

North America (58)

40

Europe (22)

20

Europe (34)

22

Asia (125)

17

North America (43)

25

Asia (25)

12

Asia (26)

9

Asia (62)

16

North America (8)

22

Asia (20)

14

Asia (12)

11

Australasia (20)

13

Subtypes within each category (where relevant)*

 

Biliary (1)

1

Bladder (16)

7

 

Cervical (359)

90

Head and neck NOS (3)

8

   

Gastric (35)

20

Prostate (194)

91

Endometrial (19)

5

Laryngeal (1)

3

Liver (40)

23

Renal (2)

1

Ovarian (19)

5

Nasopharyngeal (6)

17

Oesophagus (74)

42

Testicular (2)

1

Vaginal (2)

0.5

Oral (20)

56

Pancreas (24)

14

   

Vulval (1)

0.3

Thyroid (6)

17

 

Total participants

Range

Range

Range

Range

Range

Range

Range

Range

Range

3- 362,165

18- 184,786

14- 721,299

11- 1,198,493

15- 860,028

12- 183,000

20- 154,901

8- 1,555,000

4- 360,288

  1. *Total percentage may be greater than 100% due to rounding. NOS- not otherwise specified