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Fig. 5 | BMC Cancer

Fig. 5

From: Wilms’ tumour gene 1 (WT1) enhances non-small cell lung cancer malignancy and is inhibited by microRNA-498-5p

Fig. 5

WT1 knockdown by siRNAs inhibits NSCLC cell proliferation, survival and invasion. (A) Western blot validation of WT1 knockdown by siRNA transfection inA549 and H1299 cells. (B) Growth curves of the indicated cells assessed by CCK-8 assays. (C) Colony formation results. Representative images (left) and quantification graph (right) were provided. (D) Transwell invasion results. Representative images (left) and quantification graph (right) were provided. **P < 0.01, ***P < 0.001. Scale bar, 200 μm

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