Fig. 4

Network analysis of WT1 co-expressed genes indicates its participation in NSCLC progression. (A) Protein interaction network of WT1 co-expressed genes screened by cBioportal and plotted by STRING. (B) GO enrichment (BP: biological process, MF: molecular function, CC: cellular component) and KEGG pathway analyses of WT1 co-expressed genes. –Log₁₀ transformed false discovery rates (FDR) were plotted for each enriched functional category. (C) Western blot examination of WT1, MYC and MMP2 after WT1 siRNA transfection in A549 and H1299 cells