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Fig. 1 | BMC Cancer

Fig. 1

From: Reduced expression of phosphorylated ataxia-telangiectasia mutated gene is related to poor prognosis and gemcitabine chemoresistance in pancreatic cancer

Fig. 1

ATM/p-ATM expression and impact on prognosis of PC patients. A, PC stained with hematoxylin and eosin. B, ATM immunoreactivity was detected in PC cell nucleus (arrow), (same area as Fig. 1A). C, P-ATM immunoreactivity was detected in PC cell nucleus (arrow), (same area as Fig. 1A). Representative images of ATM expression evaluated using a score of 0 (D), 1 (E), or 2 (F). Phospho-ATM expression is scored as 0 (G), 1 (H), or 2 (I). Log-rank test survival analyses of correlation between ATM expression and OS (J) and DFS (K) in PC patients. Log-rank test survival analysis of correlation between p-ATM expression and OS (L) and DFS (M) in PC patients. IHC, immunohistochemistry; PC, pancreatic cancer; ATM, ataxia telangiectasia mutated; p-ATM, phosphorylated ATM; OS, overall survival; DFS, disease-free survival

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