Table 1 Patient characteristics stratified according to age

Age, median (IQR)

67

(57–78)

59

(51–63)

78

(74–83)

Sex, n (%)

Female

163

(40.3)

108

(48.0)

55

(30.7)

Male

241

(59.7)

117

(52.0)

124

(69.3)

BMI, n/total n (%)

< 18.5

32/400

(8.0)

18/223

(8.1)

14/177

(7.9)

18.5–23.9

206/400

(51.5)

117/223

(52.5)

89/177

(50.3)

≥ 24.0

162/400

(40.5)

88/223

(39.5)

74/177

(41.8)

ECOG performance status, n (%)

0–1

304

(75.2)

218

(96.9)

86

(48.0)

2–4

100

(24.8)

7

(3.1)

93

(52.0)

aCCI, n (%)

0–3

241

(59.7)

201

(89.3)

40

(22.3)

≥ 4

163

(40.3)

24

(10.7)

139

(77.7)

Year of diagnosis, n (%)

2009–2013

228

(56.4)

124

(55.1)

104

(58.1)

2014–2019

176

(43.6)

101

(44.9)

75

(41.9)

Histologic grade, n (%)

Well or moderately differentiated

61

(15.1)

31

(13.8)

30

(16.8)

Poorly differentiated

343

(84.9)

194

(86.2)

149

(83.2)

Signet-ring feature, n/total n (%)

No

251/403

(62.3)

114/225

(50.7)

137/178

(77.0)

Yes

152/403

(37.7)

111/225

(49.3)

41/178

(23.0)

Gastrectomy type, n (%)

Subtotal gastrectomy

274

(67.8)

163

(72.4)

111

(62.0)

Total gastrectomy

130

(32.2)

62

(27.6)

68

(38.0)

Lymphadenectomy type, n (%)

< D2 dissection

108

(26.7)

43

(19.1)

65

(36.3)

D2 dissection

296

(73.3)

182

(80.9)

114

(63.7)

Stage, n (%)

Stage II

176

(43.6)

99

(44.0)

77

(43.0)

Stage III

228

(56.4)

126

(56.0)

102

(57.0)

Lymphovascular invasion, n/total n (%)

No

112/403

(27.8)

67/224

(29.9)

45/179

(25.1)

Yes

291/403

(72.2)

157/224

(70.1)

134/179

(74.9)

Perineural invasion, n/total n (%)

No

171/399

(42.9)

86/222

(38.7)

85/177

(48.0)

Yes

228/399

(57.1)

136/222

(61.3)

92/177

(52.0)

Adjuvant chemotherapy, n (%)

No

82

(20.3)

12

(5.3)

70

(39.1)

Yes

322

(79.7)

213

(94.7)

109

(60.9)

CEA level, n/total n (%)

Normal (< 5 U/mL)

328/382

(85.9)

191/215

(88.8)

137/167

(82.0)

Elevated (≥ 5 U/mL)

54/382

(14.1)

24/215

(11.2)

30/167

(18.0)

CA 19 − 9 level, n/total n (%)

Normal (< 34 U/mL)

272/330

(82.4)

160/189

(84.7)

112/141

(79.4)

Elevated (≥ 34 U/mL)

58/330

(17.6)

29/189

(15.3)

29/141

(20.6)

NLR, n/total n (%)

≤ 2.6

211/398

(53.0)

136/221

(61.5)

75/177

(42.4)

> 2.6

187/398

(47.0)

85/221

(38.5)

102/177

(57.6)

PLR, n/total n (%)

≤ 166

203/397

(51.1)

118/220

(53.6)

85/177

(48.0)

> 166

194/397

(48.9)

102/220

(46.4)

92/177

(52.0)