Vaginal microbiome community state types and high-risk human papillomaviruses in cervical precancer and cancer in North-central Nigeria

Table 3 Results of Logistic Regression: Unadjusted and Adjusted odd ratios of the association of various exposure variables with high grades/invasive cervical cancer

Variable	Unadjusted Odds Ratio	95% CI	P-value	Adjusted Odds Ratio	95%CI	P-value
Variable	Unadjusted Odds Ratio	95% CI	P-value	N = 128	95%CI	P-value
HPV status
Low risk HPV Positive	1.1	0.33–3.48	0.905	1.56	0.39–6.26	0.526
High risk HPV positive	1.73	0.84–3.56	0.133	2.72	1.12–6.58	0.027
HPV Negative (referent)
HIV status
HIV positive	2.67	1.38–5.20	0.004	3.21	1.29-8.00	0.012
HIV Negative (Referent)
Vaginal community state type
CST-III
CST-IV	1.2	0.37–3.87	0.766	1.13	0.27–4.67	0.864
CST-I (referent)	1.79	0.63–5.04	0.272	1.31	0.39–4.41	0.666
Age in years	1.05	1.01–1.08	0.005	1.01	0.97–1.06	0.483
Years of Education completed
7–12 years
> 12 years	0.28	0.09–0.88	0.03	0.64	0.14–2.95	0.571
0–6 years (referent)	0.29	0.10–0.85	0.024	0.6	0.14–2.54	0.49
Parity (total births)
2–4	2.88	0.91–9.13	0.072	2.47	0.68-9.00	0.17
> 4	5.94	1.83–19.2	0.003	4.13	0.97–17.7	0.056
0–1 (referent)

Covariates included: Age in years, HIV status, HPV status, CSTs, years of completed education, and total number of births

ISSN: 1471-2407