Table 2 Distribution of participant characteristics by vaginal microbiome community state types
Variable | Community state types | P-value | ||
|---|---|---|---|---|
CST-I | CST-III | CST-IV | ||
N = 17 | N = 33 | N = 101 | ||
HPV status | Â | Â | Â | 0.114 |
HPV Negative | 12 (21.8) | 12 (21.8) | 31 (56.4) | Â |
Low risk HPV Positive | 0 (0.0) | 3 (23.1) | 10 (76.9) | Â |
High risk HPV positive | 5 (7.6) | 14 (21.2) | 47 (71.2) | Â |
HIV status | Â | Â | Â | 0.008 |
HIV Negative | 4 (5.0) | 23 (28.8) | 53 (66.3) | Â |
HIV Positive | 13 (18.3) | 10 (14.1) | 48 (67.6) | Â |
Age (years) | 48.8 ± 11.1 | 46.9 ± 8.5 | 52.3 ± 9.9 | 0.017 |
Education years completed | 13.9 ± 3.5 | 11.2 ± 3.5 | 9.9 ± 5.2 | 0.005 |
BMI (Kg/m2) | 30.2 ± 6.9 | 26.2 ± 5.0 | 26.0 ± 5.4 | 0.024 |
Age first sex (years) | 20.9 ± 4.6 | 18.4 ± 2.6 | 19.1 ± 4.2 | 0.105 |
Age at first pregnancy(years) | 22.5 ± 5.1 | 20.6 ± 4.3 | 20.5 ± 4.4 | 0.257 |
Total life-time sex partner(s) | 2.6 ± 2.7 | 3.4 ± 2.8 | 2.7 ± 2.0 | 0.255 |
Total years of exposure to hormonal contraception | 1.9 ± 3.4 | 2.9 ± 4.1 | 3.1 ± 4.8 | 0.681 |
Total births (parity) | Â | Â | Â | 0.16 |
0–1 | 3 (17.7) | 5 (29.4) | 9 (52.9) |  |
2–4 | 8 (12.3) | 18 (27.7) | 39 (60.0) |  |
> 4 | 4 (6.4) | 10 (15.9) | 49 (77.8) |  |
Current diagnosis of invasive cervical cancer | Â | Â | Â | 0.03 |
Yes | 1 (3.7) | 2 (7.4) | 24 (88.9) | Â |
No | 16 (13.0) | 30 (24.4) | 77 (62.6) | Â |
Post-menopausal status | Â | Â | Â | 0.087 |
Yes | 8 (14.8) | 16 (29.6) | 30 (55.6) | Â |
No | 9 (9.3) | 17 (17.5) | 71 (73.2) | Â |
Ever drunk Alcohol | Â | Â | Â | 0.897 |
Yes | 2 (7.4) | 6 (22.2) | 19 (70.4) | Â |
No | 15 (12.1) | 27 (21.8) | 82 (66.1) | Â |