Fig. 2

Relative risk by cancer site per 1 drink/day increase in alcohol intake by smoking status

* Relative risk and 95% confidence intervals (CI) per 1 drink/day increase in alcohol intake, adjusted by region, body mass index, deprivation index, educational attainment, smoking (and number of cigarettes/day in current smokers), strenuous exercise, use of oral contraceptives and menopausal hormones and stratified by year of birth and year completed recruitment questionnaire. For estimation of trends, intake categories 1-2, 3-6, 7-14, 15+ drinks/week were scored according to the mean alcohol intake at reassessment 7.8 years later (2.6, 5.5, 10.0, 17.0 drinks/week respectively). ** denotes statistically significant at the FDR threshold (0.05). † See methods for histological classification. †† Additional adjustment for age at menarche, age at first birth, parity and family history of breast cancer. § Additional adjustment for age at menarche, age at first birth and parity. Includes only women who answered no to hysterectomy at recruitment. ¶ Additional adjustment for age at menarche, age at first birth and parity. Includes only women who answered no to bilateral oophorectomy at recruitment