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Fig. 1 | BMC Cancer

Fig. 1

From: An extensive study of potential inhibitors of extracellular vesicles release in triple-negative breast cancer

Fig. 1

Study design. Considering that the heterogenous population of EVs from TNBC cells can transmit a broad range of undesirable phenotypic traits to recipient cancer and normal cells, this study investigated if the heterogenous EVs population or a sub-population is responsible; if we could block undesirable cell-to-cell communication by EVs; and, if some EVs continued to be released, would their undesirable influences on recipient cells continue. EVs were collected using ultracentrifugation-based method and extensively characterised. An imaging flow cytometry method for assessing EVs in solution was compared to the more comprehensive analysis of collected EVs. Influences of EVs on recipient cells were evaluated

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BMC Cancer

ISSN: 1471-2407

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