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Table 5 Distribution of genotype and allelic frequency of polymorphisms of XRCC1 (rs25487) according to MSI level

From: The role of heavy metals in the development of colorectal cancer

SNPs

Genotype

Group

Total

p value

MSI-H

MSI-L

MSS

  

XRCC1 (rs25487)

CC

5 (31.25)

7 (50)

45 (63.38)

57 (56.44)

0.022

 

CT

8 (50)

7 (50)

24 (33.80)

39 (38.61)

 
 

TT

3 (18.75)

0 (0)

2 (2.82)

5 (4.95)

 

Allele Frequency (%)

T

43.75

25

19.72

24.26

 
 

C

56.25

75

80.28

75.74

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