Fig. 3

Co-expression and interaction analyses of CBX family members at the gene and protein levels. A Pearson correlation of CBX family members (GEPIA). The numbers in the color block represent their correlation coefficients. B Network for CBX family protein and the 100 most frequently altered neighbor genes (GeneMANIA). Each node represented a gene, and the size of the node represented the strength of gene interaction. The color of the nodes indicated the possible function of each gene, and the color of the connecting line between the nodes represented the type of gene–gene interaction. C The Gene Ontology (GO) enrichment analysis: the top 5 terms of biological process (BP), molecular function (MF), and cellular component (CC) were shown. The yellow bar chart, BP; The green bar chart, MF; The red bar chart, CC. D The top 10 Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. P < 0.05 was considered to indicate a statistically signifificant difference. The pathways shown in Fig. 3D were obtained from the KEGG database [30,31,32]