Table 3 Multivariate analyses of OS and PFS
From: An integrated model for prognosis in vulvar squamous cell carcinoma
Variable | Overall survival | Progression-free survival | ||||
|---|---|---|---|---|---|---|
| Â | HR | 95%CI | p-value | HR | 95%CI | p-value |
Age (< 67 vs. ≥ 67 yrs) | 6.335 | 1.670 -24.031 | 0.007 | 3.051 | 1.026–9.077 | 0.045 |
Stage (I vs. II - III) | 0.755 | 0.183–3.111 | 0.697 | 0.404 | 0.099–1.652 | 0.207 |
Grade (1 vs. 2–3) | 0.996 | 0.308–3.218 | 0.994 | 1.035 | 0.371–2.888 | 0.947 |
LMN (Negative vs. Positive) | 3.045 | 0.440–21.072 | 0.259 | 7.334 | 1.319–40.768 | 0.023 |
HPV (Negative vs. Positive) | 0.101 | 0.015–0.662 | 0.017 | 0.122 | 0.025–0.600 | 0.010 |
P53 (Wildtype vs. Mutant) | 1.081 | 0.332–3.527 | 0.897 | 1.216 | 0.436–3.396 | 0.709 |
Ki-67 (Low vs. High) | 9.340 | 2.136–40.844 | 0.003 | 4.348 | 1.237–15.283 | 0.022 |
TPS (< 1% vs. ≥ 1%) | 2.180 | 0.641–7.417 | 0.212 | 2.010 | 0.729–5.543 | 0.177 |
CPS (< 1 vs. ≥ 1) | 5.357 | 0.913–31.424 | 0.062 | 5.666 | 1.072–29.943 | 0.041 |
CD8 (Low vs. High) | 0.169 | 0.042–0.682 | 0.012 | 0.204 | 0.063–0.665 | 0.008 |