Table 2 Univariate analysis of OS and PFS
From: An integrated model for prognosis in vulvar squamous cell carcinoma
Variable | Overall survival | Progression-free survival | ||||
|---|---|---|---|---|---|---|
| Â | HR | 95%CI | p-value | HR | 95%CI | p-value |
Age (< 67 vs. ≥ 67 yrs) | 3.337 | 1.164–9.565 | 0.025 | 2.192 | 0.897–5.358 | 0.085 |
Stage (I vs. II - III) | 0.829 | 0.430–1.596 | 0.574 | 0.855 | 0.476–1.539 | 0.620 |
Grade (1 vs. 2–3) | 0.664 | 0.266–1.655 | 0.379 | 0.647 | 0.293–1.428 | 0.282 |
LMN (Negative vs. Positive) | 1.269 | 0.290–5.563 | 0.752 | 2.487 | 0.833–7.429 | 0.103 |
HPV (Negative vs. Positive) | 1.775 | 0.509–6.185 | 0.368 | 2.538 | 0.750–8.592 | 0.134 |
P53 (Wildtype vs. Mutant) | 1.149 | 0.443–2.984 | 0.775 | 1.399 | 0.604–3.239 | 0.433 |
Ki-67 (Low vs. High) | 1.447 | 0.558–3.756 | 0.448 | 1.100 | 0.469–2.582 | 0.826 |
TPS (< 1% vs. ≥ 1%) | 1.442 | 0.532–3.904 | 0.472 | 1.469 | 0.610–3.534 | 0.391 |
CPS (< 1 vs. ≥ 1) | 1.890 | 0.429–8.324 | 0.400 | 2.525 | 0.586–10.880 | 0.214 |
CD8 (Low vs. High) | 0.998 | 0.368–2.703 | 0.996 | 0.682 | 0.264–1.762 | 0.430 |