Fig. 6

Validation of exosome-related mRNA-miRNA regulatory relationship. A The network shows the interaction among ACTR2, EIF6, hsa-miR-139-5p and D (blue), S (green) gene sets. B Venn diagram of shared GO terms among ACTR2, EIF6, hsa-miR-139-5p. C Kaplan–Meier survival analysis of four candidate genes in TCGA. D The candidate genes expression level in hOMF-Exo and CAFs-Exo. E PIGR, CD81, UACA and PTTG1IP expression level in tumor tissue. F PIGR, CD81, UACA and PTTG1IP expression level in Cal-27 cells. * P < 0.05; ** P < 0.01; *** P < 0.001; **** P < 0.0001