Fig. 2

Exosomes are taken up by Cal-27 and promote cell proliferation and migration. A After labelled with PKH2, hOMF-Exo and CAFs-Exo were co-cultured with Cal-27 cells for 6 h and 24 h, and observed under Laser Scanning Confocal Microscope. B Exosomes co-cultured with Cal-27 cells for 0 h, 6 h, 12 h and 24 h to observe wound healing under microscope. C The wound area results showed that exosomes co‐cultured with Cal-27 cells could promote migration ability. D CCK8 assay indicated that exosomes promote the proliferation of Cal-27. E The expression of N-cadherin, E-cadherin and Vimentin did not differ significantly between the groups. * P < 0.05; ** P < 0.01; **** P < 0.0001; ns, no significance P > 0.05