Table 4 Identification of the risk factors for development synchronous lung metastasis in patients with osteosarcoma
Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | |
Age (year) | ||||
≤ 18 | 1.00 (Reference) | |||
19–40 | 0.955 (0.352–2.592) | 0.927 | ||
≥ 41 | 1.190 (0.306–4.628) | 0.802 | ||
Gender | ||||
Male | 1.00 (Reference) | |||
Female | 0.898 (0.355–2.274) | 0.821 | ||
Tumor site | ||||
Upper limb | 1.00 (Reference) | |||
Lower limb | 0.511 (0.155–1.687) | 0.271 | ||
Spine-pelvis | 1.500 (0.224–10.036)) | 0.676 | ||
Stage T | ||||
T1 | 1.00 (Reference) | 1.00 (Reference) | ||
T2 | 1.029 (0.386–2.743) | 0.955 | 1.021 (0.374–2.79) | 0.968 |
T3 | 9.429 (1.144–77.702) | 0.037 | 11.415 (1.362–95.677) | 0.025 |
Unknown | NA | NA | NA | NA |
Bone Mets | ||||
No | 1.00 (Reference) | 1.00 (Reference) | ||
Yes | 5.882(1.563–22.143) | 0.009 | 6.437 (1.69–24.513) | 0.006 |
LDH | ||||
Normal | 1.00 (Reference) | |||
Elevated | 1.538 (0.602–3.929) | 0.368 | ||
ALP | ||||
Normal | 1.00 (Reference) | |||
Within one time | 0.815 (0.267–2.489) | 0.719 | ||
More than two times | 0.904 (0.309–2.644) | 0.853 | ||