From: The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study
Clinicopathological features | n | PGC expression | PR (%) | P value | |||
---|---|---|---|---|---|---|---|
- |  +  |  +  +  |  +  +  +  | ||||
Gender | 0.889 | ||||||
 Male | 229 | 159 | 58 | 11 | 1 | 30.6 |  |
 Female | 83 | 58 | 22 | 3 | 0 | 30.1 |  |
Age(years) | 0.471 | ||||||
 < 65 | 195 | 133 | 54 | 7 | 1 | 31.8 |  |
 ≥ 65 | 117 | 84 | 26 | 7 | 0 | 28.2 |  |
Gross classification | 0.743 | ||||||
 Ulcerative | 274 | 188 | 72 | 13 | 1 | 31.4 |  |
 Infiltrative | 11 | 10 | 1 | 0 | 0 | 9.1 |  |
 Protrusive | 14 | 11 | 3 | 0 | 0 | 21.4 |  |
Tumor size (cm) | 0.307 | ||||||
 < 4 | 121 | 83 | 29 | 8 | 1 | 31.4 |  |
 ≥ 4 | 184 | 128 | 50 | 6 | 0 | 30.4 |  |
Depth of invasion | 0.338 | ||||||
 Tis-T2 | 72 | 50 | 18 | 3 | 1 | 30.6 |  |
 T3-T4 | 240 | 167 | 62 | 11 | 0 | 30.4 |  |
Lymphatic invasion | 0.779 | ||||||
 No | 171 | 119 | 44 | 7 | 1 | 30.4 |  |
 Yes | 128 | 87 | 34 | 7 | 0 | 32.0 |  |
Lymph node metastasis | 0.026 | ||||||
 No | 89 | 55 | 25 | 8 | 1 | 38.2 |  |
 Yes | 221 | 160 | 55 | 6 | 0 | 27.6 |  |
Distant metastasis | 0.970 | ||||||
 No | 297 | 207 | 76 | 13 | 1 | 30.3 |  |
 Yes | 15 | 10 | 4 | 1 | 0 | 33.3 |  |
Differentiation |  < 0.001 | ||||||
 Poorly | 214 | 160 | 48 | 6 | 0 | 25.2 |  |
 Well & moderately | 78 | 40 | 29 | 8 | 1 | 48.7 |  |
Lauren’s classification | 0.003 | ||||||
 Intestinal-type | 120 | 71 | 40 | 8 | 1 | 40.8 |  |
 Diffuse-type | 144 | 117 | 25 | 2 | 0 | 18.7 |  |
 Mixed-type | 48 | 29 | 15 | 4 | 0 | 39.6 |  |
HER2 expression | 0.037 | ||||||
 Low (- ~ +) | 63 | 44 | 17 | 2 | 0 | 30.2 |  |
 High (+ +  ~  +  + +) | 20 | 9 | 7 | 3 | 1 | 36.1 |  |