Fig. 3
From: The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study
Preventive effects of homogenous PGC deletion on chemically-induced gastric carcinogenesis. MNU was orally administered to WT and PGC KO mice according to the schedule (A). The stomach of WT and KO mice was grossly (B) and histologically (C) observed until 68Â weeks. Gastric lesions were histologically summarized (D). Note: WT, wild-type; PKO, PGC knockout; RD, regenerative dysplasia; GD, globoid dysplasia; Well, well-differentiated adenocarcinoma; Mod, moderately differentiated adenocarcinoma; Poor, poorly differentiated carcinoma