Fig. 4

ANGPTL4 overexpression correlation with EMT. (a) Pathway analysis of 1198 DEG revealed common cancer pathways. Red = log₂FC > 0.7 and Blue = log₂FC < 0.7. (b) Wound healing assay results at 0 h (after initial wound) and 48 h MP2_NTC (pink), MP2_ANGPTL4_OE + DsiRNA_NTC (turquoise), MP2_ANGPTL4_OE_ITGB4_KD (lavender), and MP2_ANGPTL4_OE_APOL1_KD (purple). Each set was performed in triplicate or quadruplicate. (c) Time to close half the gap (t1/2 gap) for each of the four cell types is plotted. t1/2: MP2 = 57.7 h, MP2_ANGPTL4_OE = 31.6 h., MP2_ANGPTL4_OE_ITGB4_KD = 192 h., and MP2_ANGPTL4_OE_APOL1_KD = 52.96 h. P-values ≤ 0.01=**, unpaired parametric t-test